skip to content »

Lichtarge Computational Biology Lab

Houston, Texas

Lichtarge Computational Biology Lab
Lichtarge Computational Biology Lab
not shown on screen

Pre-generated ET results for 2qrvA are available

ET mapped onto the structure
UPDATE: Clicking on a residue in the structure window will highlight the corresponding position in the sequence window
ET color scale
More important Prismatic/gobstopper color scale of evolutionary importance Less important
ET mapped onto the sequence
Hover your mouse pointer over the amino acid symbol to see the residue number
Click on the amino acid letter and the corresponding residue will be highlighted on the structure as spacefill(spheres)
PAEKRKPIRV LSLFDGIATG LLVLKDLGIQ VDRYIASEVC EDSITVGMVR HQGKIMYVGD VRSVTQKHIQ EWGPFDLVIG GSPCNDLSIV NPARKGLYEG TGRLFFEFYR LLHDARPKEG DDRPFFWLFE NVVAMGVSDK RDISRFLESN PVMIDAKEVS AAHRARYFWG NLPGMNRPLA STVNDKLELQ ECLEHGRIAK FSKVRQHFPV FMNEKEDILW CTEMERVFGF PVHYTDVSNM SRLARQRLLG RSWSVPVIRH LFAPLKEYFA CV
From To

ET ranks file: ET_2qrvA.ranks

You may also use PyMOL after installing the PyETV PyMOL plugin
Pre-computed ET analysis can be downloaded directly into PyMOL using PyETV

All data files2qrvA.zip
Multiple sequence alignment2qrvA.msf (97 sequences)
Click image to download a PyMOL session file

Sequence identity tree
Hover your mouse pointer over the sequence name to see the source organism name

You may choose to run a new trace using the form below:
Show Advanced Options
Advanced Input and Parameters (Optional)
Trace Options
Real-Valued Trace (rvET) 
Optimize selection of sequences from alignment for rvET 
Position-specific gap-reducing real-valued trace 
pair-interaction ET (piET) 
BLAST
E-value cutoff:
Number of proteins to extract:
Use PSI-BLAST 
Number of PSI-BLAST iterations:
Use all sequences from all iterations of PSI-BLAST 
BLAST Database Options
Custom NCBI 
Custom UniRef90 
Custom UniRef100 
Custom SwissProt reviewed 
Sequence Selection
Restrict BLAST hits to gi#'s:
Restrict BLAST hits to # proteins:
Restrict BLAST hits to minimum e-value:
Restrict BLAST hits to maximum e-value:
Restrict BLAST hits to minimum sequence identity:
Restrict BLAST hits to maximum sequence identity:
Restrict BLAST hits to minimum fractional length to query:
Alignment & Tree
Do not remove fragments 
Fractional length used to define fragments (in relation to the query in the alignment):
Do not remove identical sequences 
Do not remove short sequences 
Fractional length used to define short sequences (in relation to the query):
Tree File (NHX format):
Custom Sequence Input (BLAST will not be used if you upload your own alignment or sequences below)
Alignment File (GCG/MSF format):
-Or- Sequences File (FASTA format):
Query name in input file (eg: query_1aca):

Warning: Running a new trace may start a BLAST search followed by alignment of the sequences, which may take up to several minutes.

Questions? Contact us.