GPCR

Difference Evolutionary Trace Server for G Protein-Coupled Class A Receptors

Select a superfamily :

Select a subfamily :

Rodriguez et al. Proc Natl Acad Sci U S A. 2010 Apr 27;107(17):7789-92. PMID: 20385837
Evolution-guided discovery and recoding of allosteric pathway specificity determinants in psychoactive bioamine receptors. PNAS Abstract[PDF].

Madabushi et al. J. Biol. Chem. 2004 279(9): 8126-32 PMID: 14660595
Evolutionary trace of G protein-coupled receptors reveals clusters of residues that determine global and class-specific functions [Abstract]. [PDF].

Representative GPCR ClassA phylogenetic tree